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- Oldfield, Radulphus B., ?-1877 (1) - Commander of the "Lyra" and the "Ariel." Rendered assistance to the Zambezi Expedition on several occasions. Was the most successful prize-getter among the East African Squadron commanders.
- Oswell, William C., 1818-1893 (78) - Explorer and hunter. Met Livingstone in South Africa in 1845, and travelled with him 1849-51. Remained close friends.
- Owen, Richard, 1804-1892 (9) - Anatomist and naturalist. Conservator of the Hunterian Museum at the Royal College of Surgeons of England 1827-56. Professor of Comparative Anatomy and Physiology 1836-56. Taught Livingstone in 1840. Superintendent of the British Museum 1856-83. Knighted 1884.